Procaine Freebase CAS 59-46-1 – High-Purity Chemical Supplier

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Global Chem Market is a reliable international supplier of Procaine Freebase (CAS No. 59-46-1), offering consistent quality and secure delivery across the United States, United Kingdom, Australia, and Europe. Our Procaine Freebase is manufactured under strict quality standards, making it suitable for laboratory, analytical, and industrial research applications.

Procaine Freebase,/ CAS 59-46-1/Procaine powder, chemical name is 4-aminobenzoic acid 2-(diethylamino)ethyl ester hydrochloride. The synthesis of Procaine typically involves several steps, primarily using p-nitrobenzoic acid as the starting material. Below is a detailed synthesis route: Raw Materials: p-nitrobenzoic acid, diethylaminoethanol, xylene (as solvent and catalyst), and an antifoaming agent.

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Procaine powder can be used as a raw material, chemical material in the laboratory. These physical properties help characterize its purity and solid-state structure. The electrical charge is neutral, so it does not have the advantages of electrostatic force and repulsive force. This limits its potential in technological applications. It is a chiral compound with both left-handed and right-handed properties. This optical activity is due to the chiral center in its molecule. The rotation of left rotation is -14.3 °, and the rotation of right rotation is+13.9 °.

It has low toxicity. When used at the correct dosage, it is usually a safe anesthetic. However, excessive or misuse can lead to toxic reactions, including death. Overall, as an anesthetic drug, the study of its physical properties is crucial for its application and production, and these characteristics will also play an important role in the fields of technology and medicine.

Chemical Formula

C13H20N2O2
M.W
236.31
Melting point 61°
Boiling point 378.78°C (rough estimate)
Density 1.0604 (rough estimate)
Refractive index 1.5430 (estimate)

Uses of Procaine Freebase CAS 59-46-1

Procaine Freebase is widely used in chemical and pharmaceutical research. It serves as an important reference compound in formulation development, analytical testing, and synthesis studies. In research environments, it is often utilized to study ester-type local anesthetics, molecular interactions, and stability behavior under various conditions. This product is intended strictly for research and laboratory use.

Available Form

Procaine Freebase CAS 59-46-1 is typically supplied as a white to off-white crystalline powder. The freebase form is characterized by its low water solubility and stability under recommended storage conditions. Global Chem Market offers customized packaging options to meet laboratory and bulk research requirements while ensuring product integrity during transit.

Side Effects and Handling Information

Procaine Freebase may cause skin, eye, or respiratory irritation if improperly handled. Direct contact or inhalation of dust should be avoided. Standard laboratory safety practices—such as the use of gloves, protective eyewear, and adequate ventilation—are strongly recommended. This compound should only be handled by trained professionals in controlled environments.

Chemistry of Procaine Freebase

Chemically, Procaine Freebase is an ester-type compound derived from para-aminobenzoic acid (PABA) and diethylaminoethanol. Its molecular structure contributes to its anesthetic classification in pharmaceutical chemistry. The freebase form differs from salt forms in solubility and reactivity, making it especially useful in chemical analysis and formulation research.

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